Chlorphenamine: what it is for, side effects, dangers and Tupi Tea Ingredients
Chlorpheniramine or
Chlorpheniramine is an anti-allergic, group of antihistamines that blocks the
effects of histamine responsible for the symptoms in cases of allergy.
Chlorphenamine manages to reduce or eliminate these symptoms.
What is chlorphenamine for?
Chlorphenamine (or
chlorferinamine) is an inhibitor of histamine receptors used in cases of
allergies due to the ingestion of medications, allergic conjunctivitis,
vasomotor rhinitis, hay fever and allergic reactions of irritation or skin
rashes. Histamine causes the symptoms of an allergic reaction such as sneezing,
red and watery eyes, inflammation, skin rashes and constant nasal flow.
It is also used to counteract
the symptoms by allergic reactions to food, insect bites or cosmetic products.
Soothes rhinitis, hives, sneezing, itching in ears, nose, eyes and throat,
consequences of allergic conditions.
What is the use of compound chlorphenamine?
In the compound
chlorphenamine, combine 2 drugs are added to the same tablet. Phenylephrine and
Acetaminophen or paracetamol. This combination allows you to control the
symptoms of the common cold more quickly, in a single presentation.
What is chlorpheniramine maleate used for?
Chlorpheniramine comes in
maleate form in all its commercial presentations, tablets, capsules or syrup.
Maleate is a chemical
functional group, derived from a malic acid salt that binds to some major
molecule. In this case it binds to chlorphenamine. by itself they have no
effect on the organism. Serves to maintain stable active ingredients in
different pharmaceutical presentations.
What is chlorphenamine syrup for?
Chlorphenamine syrup fulfills
the same functions as tablets and capsules. The presentation in syrup
facilitates dosing in children and ingestion in elderly or with difficulty to
fix tablets.
In what presentation is chlorphenamine found?
Chlorphenamine is found in
syrup, oral tablets or parenterally. It is metabolized in the liver and has a
lifetime in the blood of up to 12 hours. It is discarded in the urine.
What is the commercial name of chlorphenamine?
In Mexico, there is
Desenfriol-D, which contains 2 grams of chlorphenamine, 500 mg of paracetamol
and 5 mg of phenylephrine.
Also found is Theraflu, which
contains Chlorphenamine, paracetamol, pseudoephedrine and dextromethorphan.
They also sell it in its
generic form:
What dose of chlorphenamine to take?
The dose will depend on the
condition, weight and age of the patient. Also to the type of presentation and
its milligrams. In adults, chlorphenamine maleate is usually needed in tablets
of 4 mg, maximum of 24 mg daily, but it will be the doctor who needs the amount
to be taken.
Chlorphenamine can be obtained
alone or simply, or chlorphenamine compound that serves in cases of nasal
congestion and headache or fever, has acetaminophen and caffeine in the same
tablet.
How does chlorphenamine work in the body?
The substance blocks
histamine, idazolic amine that activates the symptoms of an allergic reaction
in the body and stops the effects of acetylcholine, which "dry up"
body fluids by reducing watery eyes or constant nasal flow.
Chlorphenamine reduces the
symptoms of the flu, but does not cure it.
Side effects of chlorphenamine
The majority of patients do
not manifest side effects to the chemical compound. In cases that do occur,
they tend to decrease progressively with the adaptation of the organism to the
substance.
Chlorpheniramine can aggravate
the symptoms of cough with phlegm in patients with chronic asthma, so it will
only be ingested if it is prescribed by a doctor.
Caution should be exercised in
its use in pregnant women. It will be used under medical supervision during
lactation.
A study by the University of
Manitoba warned of the care of this drug in elderly patients.
Also in children under 3
years, precautions must be taken. The University of Manitoba (Canada) also
reported differences in effects in children.
The following chart covers
some of the side effects of Clorfenamine and what to do about them.
The use of the compound will
be suspended and the doctor will be assisted with the following symptoms:
·
Short of breath.
·
Unusual weakness
·
Humor changes.
·
Tremors or
convulsions.
·
Little urination
or stop urinating.
·
Bruising or
bleeding.
·
Changes or
acceleration in the heart rate.
The main side effects are at
the level of the Central Nervous System as evidenced by several scientific
publications.
Immediate medical help will be
sought in cases of urticaria or rash, swelling of the face, lips, tongue,
throat or difficulty breathing.
Ideally, discuss with the
doctor if the benefits of the medication are greater than the potential adverse
effects.
Patients with hepatic
insufficiency and heart problems will not consume chlorpheniramine, since in
the second of these conditions it can cause tachycardia, sweating, tremors,
anxiety, hypotension and arrhythmia.
Alcohol will not be taken
under treatment with the drug because it depresses the nervous system and
potentiates the sedative effects, causing a powerful drowsiness.
Chlorpheniramine cannot be
ingested by any patient because it causes side effects according to age,
weight, life conditions, type of condition and medications consumed. The most
responsible will be to go to the doctor first.
Does Chlorphenamine make you sleepy?
Yes. Although individuals can
take it to sleep, it is not their accepted use for that purpose. It can not
cause drowsiness or dizziness in people susceptible to the substance, so no
machine will be driven, nor will activities that demand concentration or be
alert, during consumption.
The use of substances that
cause drowsiness or alcohol intake while being treated with Clorfenamine will
be limited. Getting up slowly after sitting or lying down will minimize
possible dizziness or lightheadedness. The importance of avoiding its use
during activities that warrant being alert and awake has been reported in the
literature.
Is chlorphenamine useful for sleeping?
This medicine produces
drowsiness, slow thinking and decreases reflex reactions of the body. In case
you have sleep problems, you benefit from taking this type of medication.
However, its main use must be
as antiallergic and for a limited time. It should not be used as a sleep
inductor alone or taken routinely for this purpose.
Dosage of chlorpheniramine
The medicine will be
administered as directed by the doctor. Your intake will not be longer than
prescribed, which is usually for a short time and depending on the presentation
administered.
The following are the usual
doses:
Children from one year to 23 months: one mg (2.5 ml) twice a day, preferably in the
mornings and afternoons.
Children from 2 to 5 years old: one mg (2.5 ml) every 4 to 6 hours. Do not exceed
more than 6 doses (6 mg) per day.
Children from 6 to 11 years old: 2 mg (5 ml) every 4 to 6 hours. Do not exceed more
than 6 doses (12 mg) per day.
Adults and children over 12 years: 4 mg (one tablet or 10 ml) every 4 to 6 hours. Do not
exceed more than 6 doses (24 mg) per day with less than 65 years or more than 3
doses (12 mg) every 24 hours with more than that age.
How to take chlorphenamine maleate?
The medication will not be
taken for more than 7 days in a row.
The patient will consult with
the doctor if the symptoms do not decrease, there are no improvements or there
are headaches, rash or fever, after that period.
Chlorphenamine will be taken
before or after food.
If the treatment is with oral
solution, the amount will be measured in a specific spoon for medicines, not
with a kitchen spoon. If the box does not have it, the pharmacist will be
asked.
Prolonged-release tablets will
not chew, break or crush. They will be swallowed complete. Fractionation can
cause a high percentage of the substance to be released at the same time.
Dosage of compound chlorphenamine
The compound chlorphenamine
contains 4 mg of its main component, with phenylephrine 5 mg, caffeine 25 mg
and paracetamol 500 mg.
The suggested dose of this
Chlorpheramine composed of 2 times a day. Do not exceed this dose
How to take compound chlorphenamine?
It should be taken in chaos of
common cold, with many nasopharyngeal symptoms and headache, at least 2 times a
day, for 7 days maximum. You can stop it by improving symptoms.
What is the use of amantadine with chlorphenamine and
paracetamol?
In Mexico, this combination is
known under the trade name Antiflus-Des.
It is indicated for cases of
Influenza A virus infections, which occur similar to the common cold with a lot
of cough, fever and nasal congestive symptoms.
What is dextromethorphan for with guaifenesin and
chlorphenamine?
This combination is used in
case of respiratory symptoms with cough and bronchial secretions.
In similar pharmacies in
Mexico you can request it under the name of Co-Exaliv.
What is the use of phenylephrine with chlorphenamine
and paracetamol?
This combination is very
similar to compound chlorphenamine, but without caffeine.
It is indicated in cases of
common cold or flu with nasal symptoms, sneezing, congestion and fever.
What is the use of chlorphenamine in syrup 50 mg / 100
ml?
Chlorphenamine in syrup has
the same antiallergic effect as in tablets, capsules or ampoules. The advantage
of the syrup is that it allows easy dosing according to weight and age in cases
of children or older adults that require lower doses. It is also useful in
cases of people with swallowing problems.
Storage and storage
The medicine will be stored at
room temperature away from heat and humidity. The oral solution should not be
frozen.
This or any other medication
will not be recommended, even if the other person's symptoms are similar,
because the health of the individual can be put at risk with fatal
consequences.
The forgotten dose will be
taken when it is remembered, but not if the next amount is close to being ingested.
Taking two doses in a row could put your health at risk.
Interaction with other medications
The interaction of a drug with
another substance can cause side effects to intensify or change the effect of
the drug in the body.
The doctor will be informed if
he is under treatment with another medicine, substance, vitamin supplement or
herbal product.
The dose of any medicine will
not be increased or decreased, nor will the use of another substance be started
or discontinued, without first consulting with the doctor.
The following are contents
that may interact with Chlorphenamine, as revealed by the World Health
Organization in its file and drug interactions:
·
Scopolamine
·
Antispasmodics:
Atropine, alkaloids, belladonna.
·
Topical antihistamines:
diphenhydramine spray, cream or ointment.
·
Tricyclic
antidepressants or drugs to treat Parkinson's syndrome: anticholinergics such
as benztropine and Trihexyphenidyl.
The label of the ingested
medicines will be reviewed because they could have ingredients that cause
drowsiness. If so, you will consult your doctor before taking Clorfenamine.
The doctor will be informed if
another substance causing drowsiness is being used as muscle relaxants
(Carisoprodol, Cyclobenzaprine), opioids or analgesics for pain (hydrocodone,
codeine), marijuana, alcohol, antihistamines (Cetirizine, Diphenhydramine) or
medications to treat anxiety. or sleep disorders (Lorazepam, Zolpidem,
Alprazolam). Tupi
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These substances could
interfere with laboratory tests.
Important considerations
Always consult your doctor if
you want to administer a cough or cold medicine in a child. The misuse of these
medicines could cause fatal consequences.
Do not take Chlorphenamine
with allergy to this substance or with enlarged prostate, problems urinating,
asthma attacks, narrow-angle glaucoma or a blockage in the stomach or
intestines.
Patients with liver or kidney
disease, asthma, emphysema or chronic bronchitis, epilepsy or any other
disorder that causes seizures, high blood pressure, hyperthyroidism, heart
disease, coronary artery disease or a tumor in the adrenal gland, will first
consult with the doctor before ingesting the chemical compound.
Although it is considered safe
for the fetus, this or any other drug will not be administered, without first
notifying the pregnancy doctor or if you are breastfeeding.
Some oral suspensions can be
sweetened with phenylalanine. The ingredients in the package will be checked if
you have phenylketonuria.
What problems does histamine cause?
Histamine causes the symptoms
of an allergic reaction such as sneezing, red and watery eyes, inflammation,
skin rashes and constant nasal discharge.
Constant exposure to allergen
types such as shellfish, pollen, animal hair and insect bites can cause
excessive production of histamine in sensitive people.
To their jobs they add:
·
To relieve the
itching of skin irritation caused by viral infections such as chicken pox.
·
To treat
anaphylaxis.
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